LOW-DOSE aspirin is taken daily by millions of us on the advice of our doctors to cut the risk of clots that can cause a heart attack or stroke - but when you take it may affect how effective it is.
Aspirin makes it harder for platelets (particles in blood that make it clot) to clump together.
Platelets are most active in the morning - the peak time for heart attacks.
A 2013 study by Leiden University Medical Centre in the Netherlands found that taking aspirin at bedtime reduced platelet activity more than taking it first thing - possibly as it gives the drug time to ward off the morning surge in platelet activity.
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