A section of the main Belfast to Derry road is to be closed at weekends as part of a dualling scheme.
Work is taking place on the A6 between Castledawson and Randalstown.
The Department of Infrastructure said the next stage of construction requires a series of weekend closures starting this Friday night.
The excavation work affects a 200 metre stretch from Moyola Bridge to just past the Brough Road.
The road will be shut from 10pm on Friday to 6am on Monday and the closures will continue until April 9 at the latest.
However, no work is planned on the bank holiday weekends March 16-19 and March 30-April 2.
Diversions are to be signed.
"The contractor has carefully programmed the works operations and arranged the traffic management in order to minimise the inconvenience to the public. However, motorists should be aware that some delays are expected and additional time should be allowed when planning any journeys," the department said.
