UTV has confirmed that its new home will be in Belfast's Harbour Estate, ending its association with the Ormeau Road after almost six decades.
The broadcaster will leave Havelock House in south Belfast next year to move to the top floor of the new City Quays 2 development.
It expects to be on-air in its new premises by June 2018.
Havelock House has been the home of UTV since the station opened in 1959 and the building also houses the company's radio station U105.
UTV was acquired by ITV plc in February last year.
Irish News columnist Anne Hailes, who worked at Ulster Television from its foundation and authored a book, Standby Studio, about the early days of the broadcaster, recalled the opening of Havelock House.
"When I joined there were 30 people there. The station was still being built, there was a boardroom and everything was live except the films.
"It was a most exciting time. The opening day was brilliant, Sir Laurence Olivier came over and there were thousands outside Havelock House.
"The people around Belfast loved Ulster Television and the people who worked in it. It is now a satellite station, and I think it's a shame."
She added: "It (Havelock House) was a living entity for many years but it is bricks and mortar to me now. Moving into a new building is exciting for all those who are there and will give them a new lease of life."
Terry Brennan, head of news and programming at UTV, said the move would make the channel "home to the most modern broadcasting centre in Europe".
In October last year, the company announced that almost a quarter of jobs were at risk of redundancy.
UTV currently employs 138 people in Belfast, with 43 jobs said to be under threat.
